First Choice Neurology

Dr. Mark Cascione joined one of the premiere private practice neurology groups, Tampa Neurology Associates, directly after completing his medical training in 1996.  After his bachelors from the College of the Holy Cross in MA, he began metabolic neuroendocrine research at the MGH in Boston before attending the Univ of Vermont College of Medicine. From his medical internship at Maine Medical Center in Portland, he moved south to complete his neurology residency and clinical neurophysiology fellowship at Duke University Medical Center in NC, and has comfortably settled in the sunshine state since then.

He credits his partners, Drs. Stephen Sergay and Susan Steen, with having the foresight to blend the clinical and academic nature of neurology with their founding of Axiom Clinical Research, in 1997. Axiom’s patient-based focus, along with Dr. Cascione’s concept of the South Tampa MS Center, which he opened in 2001, solidified his commitment to the treatment and research for people living with multiple sclerosis. When the mid-Florida chapter of the National MS Society peer counselors began to spread this news, further opportunities for patient care began to flourish in South Tampa. The methodical manner and time “Dr. C” spends with his 1200+ MS patients to assess their multiple issues allows for a high quality patient experience.   

Dr. Cascione has been the principle investigator in 50+ MS protocols, and in over 100 other neurological trials with Axiom Research, and has been its vice-president for the past ten years. He has garnered national and international MS thought-leader status and has educated other neurologists and MS specialists about treatment modalities available to the MS community, and has been a faculty advisor/lecturer and presenter at MS congresses even beyond the US in Montreal, Copenhagen, Barcelona, London and most recently in June 2019 in Buenos Aires. 

His fellow partners at Tampa Neurology, Dr. Steen, Dr. Sunil Reddy and Dr. Linga V Reddy have personal expectations to individually meet the highest of ongoing medical standards with a patient-centered focus on their neurologic care, which drives their practice forward. This has continued with the recent partnership with First Choice Neurology physicians group in 2017, now enabling broader coverage with 50+ neurologic specialists from Tampa to Miami.

A focus on physical and psychological wellness is maintained by Dr. Cascione. An avid 5 day a week gym-goer himself, the importance of regular physical exercise, healthy eating, social interactions and cognitive activities help complete patients’ neurologic care. Dr. Cascione also offers medical advice to Quantum Leap Farms horseback “hippotherapy” rehabilitation for patients with MS. Among other accolades, he was voted one of Tampa’s Top Docs in 2017 and 2018. New patients are welcome to the South Tampa office!


2919 W Swann Ave STE 401, Tampa, FL 33609 | P: 813-872-1548 |